There have been a number of fixture changes, including those brought about by Vase and FA Cup ties:

Friday 14th October 2022
Seaham Red Star v West Auckland (from 15/10)

Tuesday 18th October 2022
Whickham v Thornaby (from 04/02)

Saturday 22nd October 2022
Northallerton Town v West Allotment (from 22/04)
Bedlington Terriers v Prudhoe YCS (from 22/04)
Blyth Town v Sunderland West End (from 05/11)
Boldon CA v Boro Rangers (from 05/11)
Easington Colliery v Birtley Town (from 04/02)
Washington v Willington (from 18/02)

Tuesday 1st November 2022
Whitley Bay v Newton Aycliffe (from 22/10)

Wednesday 2nd November 2022
Northallerton Town v Bishop Auckland (from 22/10)

Friday, 4th November 2022

Easington Colliery v Brandon United (from 5/11)

Tuesday 6th December 2022
Whickham v Ashington (from 15/11)

Tuesday 27th December 2022
Prudhoe YC v Newcastle University (from 26/12)

Saturday 4th February 2023
Thornaby v Whickham (from 19/10)

Saturday 4th March 2023
Redcar Athletic v Ashington (from 04/10)
West Allotment Celtic v Thornaby (from 22/10)
Whickham v Penrith (from 22/10)
Newcastle University v Willington (from 22/04)

Friday 24th March 2023
West Auckland v Seaham Red Star (from 25/03)

Saturday 1st April 2023
Newton Aycliffe v Whitley Bay (from 11/10)
Horden CW v Boro Rangers (from 22/10)

Saturday 22nd April 2023
Prudhoe YC v Bedlington Terriers (from 22/10)
Willington v Newcastle University (from 22/10