| 2022-07-29 19:30:0029/07/22 | Blyth Town v Prudhoe YC Seniors | 1 - 5 | Division 2 | 2022-23 | Gateway Park | | 125 |
| Liam Wotherspoon (39) |
| Matthew Law (2) Sam Dibb-Fuller (16, 22) Craig Farley (61) Thomas Ions (62) |
| 2022-08-03 19:30:0003/08/22 | Prudhoe YC Seniors v Sunderland West End | 3 - 0 | Division 2 | 2022-23 | Kimberley Park | | 260 |
| Craig Fairley (10 pen) Thomas Ions (75, 83) |
| 2022-08-06 15:00:0006/08/22 | Boro Rangers v Prudhoe YC Seniors | 1 - 0 | Division 2 | 2022-23 | New Ferens Park | | 40 |
| Paul Blake (81) |
| 2022-08-09 19:30:0009/08/22 | Billingham Town v Prudhoe YC Seniors | 4 - 0 | Division 2 | 2022-23 | Bedford Terrace | | 152 |
| Ben Heeley (30) Jack Pounder (46) Karl Southern (74) Kyle Davis (85) |
| 2022-08-13 15:00:0013/08/22 | Prudhoe YC Seniors v Esh Winning | 4 - 2 | Division 2 | 2022-23 | Kimberley Park | | 92 |
| Craig Fairley (46, 58, 70) Matthew Law (88) |
| Daniel Pringle (45) Owen Lister (56) |
| 2022-08-17 19:30:0017/08/22 | Prudhoe YC Seniors v Chester-le-Street Town | 19:30:007:30 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-08-20 15:00:0020/08/22 | Ryton & Crawcrook Albion v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Kingsley Park | | |
| 2022-08-24 19:30:0024/08/22 | Prudhoe YC Seniors v Washington | 19:30:007:30 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-08-31 19:30:0031/08/22 | Prudhoe YC Seniors v Brandon United | 19:30:007:30 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-09-02 19:30:0002/09/22 | Prudhoe YC Seniors v Birtley Town | 19:30:007:30 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-09-07 19:30:0007/09/22 | Easington Colliery v Prudhoe YC Seniors | 19:30:007:30 pm | Division 2 | 2022-23 | Easington Welfare Park | | |
| 2022-09-10 15:00:0010/09/22 | Jarrow v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Perth Green CA | | |
| 2022-09-14 19:30:0014/09/22 | Prudhoe YC Seniors v Billingham Synthonia | 19:30:007:30 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-09-17 15:00:0017/09/22 | Prudhoe YC Seniors v Chester-le-Street United | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-09-20 19:30:0020/09/22 | Redcar Town v Prudhoe YC Seniors | 19:30:007:30 pm | Division 2 | 2022-23 | The Vibrant Stadium | | |
| 2022-10-01 15:00:0001/10/22 | Horden CW v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Horden Community Welfare Park | | |
| 2022-10-05 19:30:0005/10/22 | Prudhoe YC Seniors v Blyth Town | 19:30:007:30 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-10-08 15:00:0008/10/22 | Prudhoe YC Seniors v Willington | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-10-15 15:00:0015/10/22 | Boldon CA v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Boldon Colliery Welfare Ground | | |
| 2022-10-22 15:00:0022/10/22 | Prudhoe YC Seniors v Bedlington Terriers | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-10-29 15:00:0029/10/22 | Sunderland West End v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Ford Hub Sports Complex | | |
| 2022-11-12 15:00:0012/11/22 | Chester-le-Street Town v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Moor Park | | |
| 2022-11-19 15:00:0019/11/22 | Washington v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Washington FC | | |
| 2022-11-26 15:00:0026/11/22 | Brandon United v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Welfare Ground | | |
| 2022-12-03 15:00:0003/12/22 | Prudhoe YC Seniors v Billingham Town | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-12-10 15:00:0010/12/22 | Prudhoe YC Seniors v Easington Colliery | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2022-12-17 15:00:0017/12/22 | Billingham Synthonia v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Stokesley Sports Club | | |
| 2022-12-26 15:00:0026/12/22 | Prudhoe YC Seniors v Newcastle University | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-01-07 15:00:0007/01/23 | Prudhoe YC Seniors v Redcar Town | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-02-04 15:00:0004/02/23 | Prudhoe YC Seniors v Boro Rangers | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-02-11 15:00:0011/02/23 | Esh Winning v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | The WindowsPlusRoofs Arena | | |
| 2023-02-18 15:00:0018/02/23 | Prudhoe YC Seniors v Ryton & Crawcrook Albion | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-02-24 19:30:0024/02/23 | Birtley Town v Prudhoe YC Seniors | 19:30:007:30 pm | Division 2 | 2022-23 | The Arrowmark Home Improvements Stadium | | |
| 2023-03-11 15:00:0011/03/23 | Prudhoe YC Seniors v Jarrow | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-03-18 15:00:0018/03/23 | Chester-le-Street United v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | The Riverside | | |
| 2023-03-25 15:00:0025/03/23 | Prudhoe YC Seniors v Horden CW | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-04-08 15:00:0008/04/23 | Willington v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Hall Lane | | |
| 2023-04-10 15:00:0010/04/23 | Newcastle University v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-04-15 15:00:0015/04/23 | Prudhoe YC Seniors v Boldon CA | 15:00:003:00 pm | Division 2 | 2022-23 | Kimberley Park | | |
| 2023-04-22 15:00:0022/04/23 | Bedlington Terriers v Prudhoe YC Seniors | 15:00:003:00 pm | Division 2 | 2022-23 | Doctor Pit Park | | |
